Christmas is approaching, but for many scientists this is just another day at work, especially when working with live organisms. That doesn’t mean we won’t try to insert some Christmas spirit into your life in an appropriately scientific manner.
The Tallinn Christmas market with its traditional Christmas tree.
Rudolph with his red nose.
Christmas 2012 photograph of Expedition 34 crew members Thomas H. Marshburn, left, Roman Y. Romanenko, Oleg V. Novitski, Yevgeni I. Tarelkin, Kevin A. Ford, and Chris A. Hadfield [11].
You may have heard that every year BMJ has a Christmas issue with all kinds of interesting papers. Here are some recommendations, but you can find your own favorite as well.
In case your family traditions include reciting poems to Santa Claus or you’re just a fan of poetry, here are some science poems to keep everybody entertained during Christmas.
DNA holds our genetic info,It’s found within the nucleus of cells.PCR is a test that detects its presence,It can be seen through agarose gels./Elicia Fyle/
Thinking like a scientist
I want to think like a scientistObserving animals, earth or sky.I want to ask good questionsWondering how, and what, and why.
I want to make smart guessesHypothesizing what might happen and when.I want to do cool experimentsTesting my thinking again and again.
I want to write up all my data.Recording pictures, charts, or words.I want to think through all I’ve doneDrawing conclusions about what I’ve learned.
Wondering, asking, testing, concluding.This is what scientist do.If you want to think like scientistThen you must do them too!/Jennie Munson/
Winter is coming in all its glory,sunny days with glittering snowflakes,calm and frozen picturesque lakes,a perfect time to reminisce our story.
Another year has passed in hurry,lots of great without a worry,as was journey, true and kind,shared with Solis BioDyne./Taavi Ivan/
Science means to know
science means to knowbut we don't know everythingwe don't know what we don't knowand we know that we don't knowso if we don't know we should say so
unless we are ruled by egothen as our knowledge base growsthe more we know shows we have grownwe need to know more than we now knowwe can observe test evaluate our new knowstravel on the road goes slow/Andy Caldwell/
Sonnet—To Science
Science! true daughter of Old Time thou art!Who alterest all things with thy peering eyes.Why preyest thou thus upon the poet’s heart,Vulture, whose wings are dull realities?How should he love thee? or how deem thee wise,Who wouldst not leave him in his wanderingTo seek for treasure in the jewelled skies,Albeit he soared with an undaunted wing?Hast thou not dragged Diana from her car,And driven the Hamadryad from the woodTo seek a shelter in some happier star?Hast thou not torn the Naiad from her flood,The Elfin from the green grass, and from meThe summer dream beneath the tamarind tree?/Edgar Allan Poe/
Here comes the Solis sledge,filled with tech, oh cutting-edge!It drives on joy, hard work and passion.At the wheel, a christmas man of fashion,showing off his christmas bagand yelling wildly „Stability TAAAAG“!/Karl Rene Kõlvart/
[1] History.com Editors. (2017). Saturnalia. Retrieved 17 December 2021, from https://www.history.com/topics/ancient-rome/saturnalia[2] Welscher, A. (2020). O Christmas trees, O Christmas trees... Retrieved 17 December 2021, from https://eng.lsm.lv/article/culture/culture/o-christmas-trees-o-christmas-trees.a385353/[3] History.com Editors. (2009). History of Christmas Trees. Retrieved 17 December 2021, from https://www.history.com/topics/christmas/history-of-christmas-trees[4] Schwarcz, J. (2019). Celebrating Christmas With Science. Retrieved 17 December 2021, from https://www.mcgill.ca/oss/article/history/celebrating-christmas-science[5] Bump, P. (2019). The breathtaking scale of Santa Claus’s task on Christmas Eve. Retrieved 17 December 2021, from https://www.washingtonpost.com/lifestyle/2019/12/20/breathtaking-scale-santa-clauss-task-christmas-eve/[6] Nicolosi, J. (2014). Is Santa Real? (A Scientific Analysis) [Video]. YouTube: It's Okay To Be Smart. https://www.youtube.com/watch?v=dCOf6Su0Yvw&t=338s[7] Are Santa's Reindeer Males? (2017). Retrieved 17 December 2021, from https://www.livescience.com/32149-are-santas-reindeer-males.html[8] Ince, C., van Kuijen, A., Milstein, D., Yuruk, K., Folkow, L., Fokkens, W., & Blix, A. (2012). Why Rudolph's nose is red: observational study. BMJ, 345, e8311-e8311. doi: 10.1136/bmj.e8311[9] Kemp, M. Science in culture. Nature 426, 768 (2003). https://doi.org/10.1038/426768a[10] Who invented electric Christmas lights? (2019). Retrieved 17 December 2021, from https://www.loc.gov/everyday-mysteries/item/who-invented-electric-christmas-lights/[11] Uri, J. (2020). Space Station 20th: Celebrating the Holidays in Space. Retrieved 17 December 2021, from https://www.nasa.gov/feature/space-station-20th-celebrating-the-holidays-in-space[12] Burke, E. (2016). 12 facts you didn’t know about Christmas. Retrieved 17 December 2021, from https://www.siliconrepublic.com/innovation/christmas-traditions-facts[13] Coleman E, Arundel C, Clark L, Doherty L, Gillies K, Hewitt C et al. Bah humbug! Association between sending Christmas cards to trial participants and trial retention: randomised study within a trial conducted simultaneously across eight host trials BMJ 2021; 375 :e067742 doi:10.1136/bmj-2021-067742[14] Fox S T, Reid N, Tornvall I, Weerasekera S, Gordon E, Hubbard R E et al. Anticipating the ageing trajectories of superheroes in the Marvel cinematic universe BMJ 2021; 375 :e068001 doi:10.1136/bmj-2021-068001[15] Brennan P A, Oeppen R S. Delivering human factors at Christmas: how does Father Christmas do it? BMJ 2020; 371 :m4708 doi:10.1136/bmj.m4708[16] Razaeian S, Wiese B, Zhang D, Harb A, Krettek C, Hawi N et al. Nonsensus in the treatment of proximal humerus fractures: uncontrolled, blinded, comparative behavioural analysis between Homo chirurgicus accidentus and Macaca sylvanus BMJ 2020; 371 :m4429 doi:10.1136/bmj.m4429[17] Zimerman A, Worsham C, Woo J, Jena A B. The need for speed: observational study of physician driving behaviors BMJ 2019; 367 :l6354 doi:10.1136/bmj.l6354[18] Yeh R W, Valsdottir L R, Yeh M W, Shen C, Kramer D B, Strom J B et al. Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial BMJ 2018; 363 :k5094 doi:10.1136/bmj.k5094[19] Mason F, Farley A, Pallan M, Sitch A, Easter C, Daley A J et al. Effectiveness of a brief behavioural intervention to prevent weight gain over the Christmas holiday period: randomised controlled trial BMJ 2018; 363 :k4867 doi:10.1136/bmj.k4867[20] Park J J, Coumbe B G T, Park E H G, Tse G, Subramanian S V, Chen J T et al. Dispelling the nice or naughty myth: retrospective observational study of Santa Claus BMJ 2016; 355 :i6355 doi:10.1136/bmj.i6355[21] Hougaard A, Lindberg U, Arngrim N, Larsson H B W, Olesen J, Amin F M et al. Evidence of a Christmas spirit network in the brain: functional MRI study BMJ 2015; 351 :h6266 doi:10.1136/bmj.h6266[22] Ramagopalan S V, Knight M, Ebers G C, Knight J C. Origins of magic: review of genetic and epigenetic effects BMJ 2007; 335 :1299 doi:10.1136/bmj.39414.582639.BE
Lyophilization, also known as freeze-drying, is in simple terms a water-removal process that increases product stability and preserves its functionality. Our new SolisFAST® Lyo-Ready qPCR Kit with UNG represents an optimized lyophilization-compatible qPCR solution to enhance the simplicity, convenience, and speed of diagnostic and applied testing.
The running joke with PCR is that if something can go wrong, it will go wrong. Quite often it’s even impossible to determine why some samples turned out fine while the others did not. In a situation like this, it would be amazing to know some trick or a secret to avoid spending all the time and resources to do the experiment again. Here are a few we are willing to share so that you could find love for PCR.
In research, every day different methods are used to discover something new, whether it is a new disease, medicine, or something else. Often these methods were developed long ago and are confirmed to be doing what they are supposed to do. However, as technology develops so do new methods. This is exactly what Professor Steven Williams’ lab is doing at Smith College – developing new methods to be used in research and diagnostics.
As an alternative to PCR, the loop-mediated isothermal amplification (LAMP) reaction has been developed for DNA detection. The LAMP test is fast, simple, and sensitive.