Enterprise Estonia supported the project "Development of a POC test for rapid diagnosis of pathogens (incl. COVID-19)". The project period is 01.02.2021-31.12.2023.
So far, Solis BioDyne has offered the gold standard solutions for diagnostics- RT-qPCR. Now, SARS-CoV-2 has highlighted the need for a wider variety of methods for COVID-19 analysis of patient samples.
As part of the European Regional Development Fund-supported project, Solis BioDyne is developing an innovative isothermal polymerase from which a number of reagents are being developed for use in various methods. Isothermal polymerases are increasingly used in close-up patient studies for the rapid analysis of various pathogens, allowing the analysis to be performed within 30 minutes without complex equipment.
The second goal of the project is the development of freeze-drying technology for Solis BioDyne products. Freeze-drying makes it possible to significantly extend the shelf life of products and to create new types of analytical methods. The total cost of the project is 1,368,200 €, of which the European Regional Development Fund covers up to 1,094,560€.
Lyophilization, also known as freeze-drying, is in simple terms a water-removal process that increases product stability and preserves its functionality. Our new SolisFAST® Lyo-Ready qPCR Kit with UNG represents an optimized lyophilization-compatible qPCR solution to enhance the simplicity, convenience, and speed of diagnostic and applied testing.
The running joke with PCR is that if something can go wrong, it will go wrong. Quite often it’s even impossible to determine why some samples turned out fine while the others did not. In a situation like this, it would be amazing to know some trick or a secret to avoid spending all the time and resources to do the experiment again. Here are a few we are willing to share so that you could find love for PCR.
In research, every day different methods are used to discover something new, whether it is a new disease, medicine, or something else. Often these methods were developed long ago and are confirmed to be doing what they are supposed to do. However, as technology develops so do new methods. This is exactly what Professor Steven Williams’ lab is doing at Smith College – developing new methods to be used in research and diagnostics.
As an alternative to PCR, the loop-mediated isothermal amplification (LAMP) reaction has been developed for DNA detection. The LAMP test is fast, simple, and sensitive.